Chapter 13

Lecture Videos #

A Massive Open Online Course on Computational Systems Biology, which is in part, a basis for this book, is also available, through the Indian educational platforms, NPTEL (National Programme on Technology Enhanced Learning) and SWAYAM.

The lectures (including hands-on lab sessions), totalling over 30 hours of content, are also available on YouTube.

Chapter 13: Robustness and evolvability of biological systems #

Robustness in Biological Systems (15:16)

  • Overview

Robustness in Biological Systems: Mechanisms (10:47)

  • System Control
  • Redundancy
  • Modularity and Decoupling
  • Hierarchies and Protocols

Robustness in Biological Systems: Organising Principles (15:04)

  • Bow-Tie structure

Robustness in Biological Systems: Trade-offs (10:12)

  • “Robustness, Fragility and Complexity”
  • Highly Optimised Tolerance
  • Robustness and Evolvability

Robustness and Evolvability (11:29)

  • Parametric Robustness
  • `Topological' Robustness
  • Evolvability

Robustness and Evolvability (24:50)

  • Neutral Networks
  • Genotype–Phenotype Mapping