Chapter 9

Lecture Videos #

A Massive Open Online Course on Computational Systems Biology, which is in part, a basis for this book, is also available, through the Indian educational platforms, NPTEL (National Programme on Technology Enhanced Learning) and SWAYAM.

The lectures (including hands-on lab sessions), totalling over 30 hours of content, are also available on YouTube.

Chapter 9: Extending constraint-based approaches #

Other Constraint-Based Approaches (17:41)

  • Minimisation of Metabolic Adjustment

Other Constraint-Based Approaches (12:02)

  • Regulatory On-Off Minimisation

Elementary Modes (16:19)

  • Definitions
  • Simple Examples

Elementary Modes (13:09)

  • Another Example

$^{13}$C-Metabolic Flux Analysis using Mass Spectrometry (11:27)

  • Introduction to $^{13}C$-MFA

$^{13}$C-Metabolic Flux Analysis using Mass Spectrometry (11:55)

  • Methodology
  • GC-MS Analysis

$^{13}$C-Metabolic Flux Analysis using Mass Spectrometry (12:31)

  • Data Analysis
  • An Example

Lab: $^{13}$C-Metabolic Flux Analysis using Mass Spectrometry (32:27)

  • Recap
  • Simple Exercises