Chapter 14: Epilogue: The road ahead #

The past 200 years in diabetes
Polonsky (2012) The New England Journal of Medicine

An interesting perspective on two centuries of diabetes.

Physiological regulation of the pancreatic β-cell: functional insights for understanding and therapy of diabetes
McClenaghan (2007) Experimental Physiology

A detailed overview of pancreatic β-cell regulation, with insights into drug targets and mechanisms.

Insulin: discovery and controversy
Rosenfeld (2002) Clinical Chemistry

An interesting read on insulin.

The impact of mathematical modeling on the understanding of diabetes and related complications
Ajmera et al. (2013) CPT: Pharmacometrics & Systems Pharmacology

A solid review on applications of QSP for diabetes modelling.

Simulating a Living Cell
Covert (2014) Scientific American

An easy-to-read review on whole-cell modelling.

A Whole-Cell Computational Model Predicts Phenotype from Genotype
Karr et al. (2012) Cell

The classic whole-cell model of Mycoplasma genitalium.

Bridging the gaps in systems biology
Cvijovic et al. (2014) Molecular Genetics and Genomics

A nice overview of the field of systems biology.