Computational Systems Biology Lab

Mycobacterium tuberculosis (Mtb) lipid–mediated lysosomal rewiring in infected macrophages modulates intracellular Mtb trafficking and survival

Kuldeep Sachdeva, Manisha Goel, Malvika Sudhakar, Mansi Mehta, Rajmani Raju, Karthik Raman, Amit Singh, Varadharajan Sundaramurthy*,

Journal of Biological Chemistry

295:9192-9210

Elucidating the biosynthetic pathways of volatile organic compounds in Mycobacterium tuberculosis through a computational approach

Purva Bhatter, Karthik Raman*, Vani Janakiraman*,

Molecular BioSystems

13:750-755

A systems perspective of host--pathogen interactions: prediction of tuberculosis disease outcome

Karthik Raman, Ashwini Gurudas Bhat, Nagasuma Chandra,

Molecular BioSystems

6:516-530

Systems Biology of Tuberculosis: Insights for drug discovery

Karthik Raman, Nagasuma Chandra,

Understanding the Dynamics of Biological Systems: Lessons Learned from Integrative Systems Biology

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Strategies for efficient disruption of metabolism in Mycobacterium tuberculosis from network analysis

Karthik Raman, Rohit Vashisht, Nagasuma Chandra,

Molecular BioSystems

5:1740-1751

Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance

Karthik Raman, Nagasuma Chandra,

BMC Microbiology

8:234

targetTB: A target identification pipeline for Mycobacterium tuberculosis

Karthik Raman, Yeturu Kalidas, Nagasuma Chandra,

BMC Systems Biology

2:109

Hallmarks of Mycolic Acid Biosynthesis: A Comparative Genomics Study

Karthik Raman, Preethi Rajagopalan, Nagasuma Chandra,

Proteins: Structure, Function and Bioinformatics

69:358

Flux Balance Analysis of Mycobacterium tuberculosis: targets for anti-tubercular drugs

Karthik Raman, Preethi Rajagopalan, Nagasuma Chandra,

PLoS Computational Biology

1:e46