Synthetic Lethals

publications

Publication Image
 Understanding flux switching in metabolic networks through an analysis of synthetic lethals

Sowmya Manojna Narasimha†, Tanisha Malpani†, Omkar S. Mohite, J. Saketha Nath, Karthik Raman*,

npj Systems Biology and Applications

 10:104
 
Publication Image
 Metabolite systems profiling identifies exploitable weaknesses in retinoblastoma

Swagatika Sahoo*, Ranjith Kumar R, Brandon Nicolay, Omkar Mohite, Karthikeyan Sivaraman, Vikas Khetan, Pukhraj Rishi, Suganeswari Ganesan, Subramanian Krishnakumar, Karthik Raman, Wayne Miles, Sailaja V Elchuri*,

FEBS Letters

 593:23-41
 
Publication Image
 Understanding the evolution of functional redundancy in metabolic networks

Gayathri Sambamoorthy, Karthik Raman*,

Bioinformatics

 34:i981-i987
 
Publication Image
 Computational Prediction of Synthetic Lethals in Genome-Scale Metabolic Models Using Fast-SL

Karthik Raman*, Aditya Pratapa, Omkar Mohite, Shankar Balachandran,

Methods Mol Biol

 1716:315-336
 
Publication Image
 Fast-SL: An efficient algorithm to identify synthetic lethal sets in metabolic networks

Aditya Pratapa, Shankar Balachandran, Karthik Raman*,,

Bioinformatics

 31:3299-3305