Computational Systems Biology Lab

Understanding flux switching in metabolic networks through an analysis of synthetic lethals

Sowmya Manojna Narasimha†, Tanisha Malpani†, Omkar S. Mohite, J. Saketha Nath, Karthik Raman*,

npj Systems Biology and Applications

10:104

Panera: A novel framework for surmounting uncertainty in microbial community modelling using Pan-genera metabolic models

Indumathi Palanikumar, Himanshu Sinha, Karthik Raman*,

iScience

27:110358

Designing function-specific minimal microbiomes from large microbial communities

Aswathy Raghu, Indumathi Palanikumar, Karthik Raman*,

npj Systems Biology and Applications

10:46

Effect of Dormant Spare Capacity on the Attack Tolerance of Complex Networks

Sai Saranga Das, Karthik Raman,

Physica A

598:127419

A Computational Framework to Identify Metabolic Engineering Strategies for the Co-Production of Metabolites

Lavanya Raajaraam, Karthik Raman*,

Frontiers in Bioengineering and Biotechnology

9:779405

Two-species community design of lactic acid bacteria for optimal production of lactate

Maziya Ibrahim, Karthik Raman*,

Computational and Structural Biotechnology Journal

19:6039-6049

MinReact: a systematic approach for identifying minimal metabolic networks

Gayathri Sambamoorthy, Karthik Raman*,

Bioinformatics

36:4309-4315

Adapting Community Detection Algorithms for Disease Module Identification in Heterogeneous Biological Networks

Beethika Tripathi, Srinivasan Parthasarathy, Himanshu Sinha, Karthik Raman, Balaraman Ravindran*,

Frontiers in Genetics

10:164

Enumerating all possible biosynthetic pathways from metabolic networks

Aarthi Ravikrishnan, Meghana Nasre, Karthik Raman*,

Scientific Reports

8:9932

Computational Prediction of Synthetic Lethals in Genome-Scale Metabolic Models Using Fast-SL

Karthik Raman*, Aditya Pratapa, Omkar Mohite, Shankar Balachandran,

Methods Mol Biol

1716:315-336

Predicting Novel Metabolic Pathways through Subgraph Mining

Aravind Sankar, Sayan Ranu*, Karthik Raman*,

Bioinformatics

33:3955-3963

Fast-SL: An efficient algorithm to identify synthetic lethal sets in metabolic networks

Aditya Pratapa, Shankar Balachandran, Karthik Raman*,,

Bioinformatics

31:3299-3305